Mehmet Kaya

(BBB) health and disease in rodent models, experimentally induced pathological conditions in rodents, including sepsis, epilepsy, hypertension, diabetes, and traumatic brain injury, behavior of barrier type of brain capillary endothelial cells in these disease models. The determine putative mechanisms which may enable the treatment drugs 98% of which are unable to pass in to the brain tissue owing to a functioning BBB, to permeate into the brain by physiological manipulations for opening the BBB for a desired period and subsequently closing the barrier.